Publications

2023

  • Light-Fueled Primitive Replication and Selection in Biomimetic Chemical Systems. Bartus, É.; Tököli, A.; Mag, B.; Bajcsi, Á.; Kecskeméti, G.; Wéber, E.; Kele, Z.; Fenteany, G.; Martinek, T. A. J. Am. Chem. Soc. 2023, 145, 13371-13383. https://pubs.acs.org/doi/pdf/10.1021/jacs.3c03597

  • Improved Metal-Free Approach for the Synthesis of Protected Thiol Containing Thymidine Nucleoside Phosphoramidite and Its Application for the Synthesis of Ligatable Oligonucleotide Conjugates. Kupihár, Z.; Ferenc, G.; Petrovicz, V. L.; Fáy, V. R.; Kovács, L.; Martinek, T. A.; Hegedüs, Z. Pharmaceutics 2023, 15 (1), 248. https://doi.org/10.3390/pharmaceutics15010248

  • Structural Adaptation of the Single-Stranded DNA-Binding Protein C-Terminal to DNA Metabolizing Partners Guides Inhibitor Design. Tököli, A.; Bodnár, B.; Bogár, F.; Paragi, G.; Hetényi, A.; Bartus, É.; Wéber, E.; Hegedüs, Z.; Szabó, Z.; Kecskeméti, G. Pharmaceutics 2023, 15 (4), 1032. https://www.mdpi.com/1999-4923/15/4/1032

2022

  • Tilted State Population of Antimicrobial Peptide PGLa Is Coupled to the Transmembrane Potential. Németh, L. J.; Martinek, T. A.; Jójárt, B. J. Chem. Inf. Model. 2022, 62 (20), 4963–4969. https://pubs.acs.org/doi/full/10.1021/acs.jcim.2c00667

  • Rationally Designed Foldameric Adjuvants Enhance Antibiotic Efficacy: Via Promoting Membrane Hyperpolarization. Bhaumik, K. N.; Hetényi, A.; Olajos, G.; Martins, A.; Spohn, R.; Németh, L.; Jojart, B.; Szili, P.; Dunai, A.; Jangir, P. K.; Daruka, L.; Földesi, I.; Kata, D.; Pál, C.; Martinek, T. A. Mol. Syst. Des. Eng. 2022, 7 (1), 21–33. https://doi.org/10.1039/d1me00118c.
  • α/β-Peptides as Nanomolar Triggers of Lipid Raft-Mediated Endocytosis through GM1 Ganglioside Recognition. Hetényi, A.; Szabó, E.; Imre, N.; Bhaumik, K. N.; Tököli, A.; Füzesi, T.; Hollandi, R.; Horvath, P.; Czibula, Á.; Monostori, É.; Deli, M. A.; Martinek, T. A. Pharmaceutics 2022, 14 (3). https://doi.org/10.3390/pharmaceutics14030580.
  • Phosphine(III)-Triggered One-Pot Domino Sequences towards 5,6-Dihydropyridine-2-(1H)-One and Pyridine-2(1H)-One Scaffolds. Makra, Z.; Madácsi, R.; Martinek, T. A.; Bényei, A.; Puskás, L. G.; Gyuris, M.; Kanizsai, I. Adv. Synth. Catal. 2022, 364 (6), 1134–1143. https://doi.org/10.1002/adsc.202101370.
  • Promiscuity Mapping of the S100 Protein Family Using a High-Throughput Holdup Assay. Simon, M. A.; Bartus, É.; Mag, B.; Boros, E.; Roszjár, L.; Gógl, G.; Travé, G.; Martinek, T. A.; Nyitray, L. Sci. Rep. 2022, 12 (1), 5904. https://doi.org/10.1038/s41598-022-09574-2.

2021

  • FEHÉRJE MÉRETŰ MOLEKULÁK HUMÁN SEJTEKBE JUTTATÁSA LIPID-RAFT MEDIÁLT ENDOCITÓZISSAL. Hetényi, A.; Imre, N.; Szabó, E.; Bodnár, B.; Szkalisity, A.; Gróf, I.; Bocsik, A.; Deli, A. M.; Horváth, P.; Czibula, Á.; Monostori, É.; Martinek, T. BIOKÉMIA A Magy. BIOKÉMIAI EGYESÜLET FOLYÓIRATA 2021, 45 (4), 17–67
  • DPP-4 Cleaves α/β-Peptide Bonds: Substrate Specificity and Half-Lives. Turalić, A.; Đeđibegović, J.; Hegedüs, Z.; Martinek, T. A. ChemBioChem 2020, 21 (14), 2060–2066. https://doi.org/10.1002/cbic.202000050.

 

2020

  • Routing Nanomolar Protein Cargoes to Lipid Raft-Mediated/Caveolar Endocytosis through a Ganglioside GM1-Specific Recognition Tag. Imre, N.; Hetényi, A.; Szabó, E.; Bodnár, B.; Szkalisity, A.; Gróf, I.; Bocsik, A.; Deli, M. A.; Horvath, P.; Czibula, Á.; Monostori, É.; Martinek, T. A. Adv. Sci. 2020, 7 (4). https://doi.org/10.1002/advs.201902621.
  • Proteomimetic Surface Fragments Distinguish Targets by Function. Tököli, A.; Mag, B.; Bartus, É.; Wéber, E.; Szakonyi, G.; Simon, M. A.; Czibula, Á.; Monostori, É.; Nyitray, L.; Martinek, T. A. Chem. Sci. 2020, 11 (38), 10390–10398. https://doi.org/10.1039/d0sc03525d.
  • An Electrophilic Warhead Library for Mapping the Reactivity and Accessibility of Tractable Cysteines in Protein Kinases. Petri, L.; Egyed, A.; Bajusz, D.; Imre, T.; Hetényi, A.; Martinek, T.; Ábrányi-Balogh, P.; Keserű, G. M. Eur. J. Med. Chem. 2020, 207. https://doi.org/10.1016/j.ejmech.2020.112836.

2019

  • Multilevel Structure–Activity Profiling Reveals Multiple Green Tea Compound Families That Each Modulate Ubiquitin-Activating Enzyme and Ubiquitination by a Distinct Mechanism. Fenteany, G.; Gaur, P.; Hegedűs, L.; Dudás, K.; Kiss, E.; Wéber, E.; Hackler, L.; Martinek, T.; Puskás, L. G.; Haracska, L. Sci. Rep. 2019, 9 (1), 12801. https://doi.org/10.1038/s41598-019-48888-6.

  • Dual Action of the PN159/KLAL/MAP Peptide: Increase of Drug Penetration across Caco-2 Intestinal Barrier Model by Modulation of Tight Junctions and Plasma Membrane Permeability. Bocsik, A.; Gróf, I.; Kiss, L.; Ötvös, F.; Zsíros, O.; Daruka, L.; Fülöp, L.; Vastag, M.; Kittel, Á.; Imre, N.; Martinek, T. A.; Pál, C.; Szabó-Révész, P.; Deli, M. A. Pharmaceutics 2019, 11 (2). https://doi.org/10.3390/pharmaceutics11020073.

  • Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations. Szili, P.; Draskovits, G.; Révész, T.; Bogár, F.; Balogh, D.; Martinek, T.; Daruka, L.; Spohn, R.; Vásárhelyi, B. M.; Czikkely, M.; Kintses, B.; Grézal, G.; Ferenc, G.; Pál, C.; Nyerges, Á. Antimicrob. Agents Chemother. 2019, 63 (9). https://doi.org/10.1128/AAC.00207-19.

2018

  • Antibiotic-Resistant Bacteria Show Widespread Collateral Sensitivity to Antimicrobial Peptides. Lázár, V.; Martins, A.; Spohn, R.; Daruka, L.; Grézal, G.; Fekete, G.; Számel, M.; Jangir, P. K.; Kintses, B.; Csörgo, B.; Nyerges, Á.; Györkei, Á.; Kincses, A.; Dér, A.; Walter, F. R.; Deli, M. A.; Urbán, E.; Hegedus, Z.; Olajos, G.; Méhi, O.; Bálint, B.; Nagy, I.; Martinek, T. A.; Papp, B.; Pál, C. Nat. Microbiol. 2018, 3 (6), 718–731. https://doi.org/10.1038/s41564-018-0164-0.
  • Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers. Bartus, É.; Olajos, G.; Schuster, I.; Bozsó, Z.; Deli, M. A.; Veszelka, S.; Walter, F. R.; Datki, Z.; Szakonyi, Z.; Martinek, T. A.; Fülöp, L. Molecules 2018, 23 (10). https://doi.org/10.3390/molecules23102523.
  • Jelölésmentes kölcsönhatásmérés. In Ezerarcú fehérjék; Buday, L., Nyitray, L., Perczel, A., Eds.; Semmelweis Kiadó és Multimédia Stúdió: Budapest, 2018; pp 25–485
  • NMR- és ESR-spektroszkópia. In Ezerarcú fehérjék; Buday, L., Nyitray, L., Perczel, A., Eds.; Semmelweis Kiadó és Multimédia Stúdió: Budapest, 2018; pp 54–203
  • Peripheral Cyclic β-Amino Acids Balance the Stability and Edge-Protection of β-Sandwiches. Olajos, G.; Hetényi, A.; Wéber, E.; Szögi, T.; Fülöp, L.; Martinek, T. A. Org. Biomol. Chem. 2018, 16 (30), 5492–5499. https://doi.org/10.1039/c8ob01322e.

2017

  • De Novo Modular Development of a Foldameric Protein–Protein Interaction Inhibitor for Separate Hot Spots: A Dynamic Covalent Assembly Approach. Bartus, É.; Hegedüs, Z.; Wéber, E.; Csipak, B.; Szakonyi, G.; Martinek, T. A. ChemistryOpen 2017, 6 (2), 236–241. https://doi.org/10.1002/open.201700012.
  • Molecular Recognition Using Foldamers. In Comprehensive Supramolecular Chemistry II; Jerry, A., George, W. G., Len, B., Eds.; Reference Module in Chemistry, Molecular Sciences and Chemical Engineering; Elsevier: Oxford, 2017; Vol. 4, pp 511–537. https://doi.org/10.1016/B978-0-12-409547-2.12547-8.
  • Loop-F of the α-Subunit Determines the Pharmacologic Profile of Novel Competitive Inhibitors of GABAAreceptors. Mihalik, B.; Pálvölgyi, A.; Bogár, F.; Megyeri, K.; Ling, I.; Barkóczy, J.; Bartha, F.; Martinek, T. A.; Gacsályi, I.; Antoni, F. A. Eur. J. Pharmacol. 2017, 798, 129–136. https://doi.org/10.1016/j.ejphar.2017.01.033.
  • Multivalent Foldamer-Based Affinity Assay for Selective Recognition of Aβ Oligomers. Olajos, G.; Bartus, É.; Schuster, I.; Lautner, G.; Gyurcsányi, R. E.; Szögi, T.; Fülöp, L.; Martinek, T. A. Anal. Chim. Acta 2017, 960, 131–137. https://doi.org/10.1016/j.aca.2017.01.013.

2016

  • Foldameric Probes for Membrane Interactions by Induced β-Sheet Folding. Hegedüs, Z.; Makra, I.; Imre, N.; Hetényi, A.; Mándity, I. M.; Monostori, É.; Martinek, T. A. Chem. Commun. 2016, 52 (9), 1891–1894. https://doi.org/10.1039/c5cc09257d.
  • Target-Specific NMR Detection of Protein–Ligand Interactions with Antibody-Relayed 15N-Group Selective STD. Hetényi, A.; Hegedűs, Z.; Fajka-Boja, R.; Monostori, É.; Kövér, K. E.; Martinek, T. A. J. Biomol. NMR 2016, 66 (4), 227–232. https://doi.org/10.1007/s10858-016-0076-3.
  • Competitive Inhibition of TRPV1–Calmodulin Interaction by Vanilloids. Hetényi, A.; Németh, L.; Wéber, E.; Szakonyi, G.; Winter, Z.; Jósvay, K.; Bartus, É.; Oláh, Z.; Martinek, T. A. FEBS Lett. 2016, 590 (16), 2768–2775. https://doi.org/10.1002/1873-3468.12267.

2015

  • Two-Stage Interaction of the Tumor Nursing Galectin-1 with the Antiangiogenic Peptide Anginex. Hegedüs, Z.; Wéber, E.; Végh, L.; Váczi, B.; Tubak, V.; Kriston-Pál, É.; Kele, Z.; Monostori, É.; Martinek, T. A. J. Therm. Anal. Calorim. 2015, 120 (1), 449–456. https://doi.org/10.1007/s10973-014-4031-9.
  • Peptides and Peptidomimetics for the Therapy of Neurodegenerative Diseases and Use Thereof., 2015
  • Induced Folding of Protein-Sized Foldameric β-Sandwich Models with Core β-Amino Acid Residues. Olajos, G.; Hetényi, A.; Wéber, E.; Németh, L. J.; Szakonyi, Z.; Fülöp, F.; Martinek, T. A. Chem. - A Eur. J. 2015, 21 (16), 6173–6180. https://doi.org/10.1002/chem.201405581.

2014

  • Predicting Order and Disorder for β-Peptide Foldamers in Water. Németh, L. J.; Hegedüs, Z.; Martinek, T. A. J. Chem. Inf. Model. 2014, 54 (10), 2776–2783. https://doi.org/10.1021/ci5003476.
  • Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry. Cabrele, C.; Martinek, T. A.; Reiser, O.; Berlicki, Ł. J. Med. Chem. 2014, 57 (23), 9718–9739. https://doi.org/10.1021/jm5010896.

2013

  • Foldameric α/β-Peptide Analogs of the β-Sheet-Forming Antiangiogenic Anginex: Structure and Bioactivity. Hegedüs, Z.; Wéber, E.; Kriston-Pál, É.; Makra, I.; Czibula, Á.; Monostori, É.; Martinek, T. A. J. Am. Chem. Soc. 2013, 135 (44), 16578–16584. https://doi.org/10.1021/ja408054f.
  • Peptides Containing Cis-2-Aminocyclopentanecarboxylic Acid Residues - Structure and Biological Activity. Berlicki, L.; Wojcik, P.; Pilsl, L.; Kaske, M.; Bernhardt, G.; Martinek, T.; Cabreie, C.; Reiser, O. Biopolymers 2013, 100 (3), 274-274 PG – 1
  • Foldameric β-H18/20P Mixed Helix Stabilized by Head-to-Tail Contacts: A Way to Higher-Order Structures. Szolnoki, É.; Hetényi, A.; Mándity, I. M.; Fülöp, F.; Martinek, T. A. European J. Org. Chem. 2013, 2013 (17), 3555–3559. https://doi.org/10.1002/ejoc.201201633.
  • Peptidic Foldamers: Ramping up Diversity. Martinek, T. A.; Fülöp, F. Chem. Soc. Rev. 2012, 41 (2), 687–702. https://doi.org/10.1039/c1cs15097a.

2012

  • Unique α,β- and α,α,β,β-Peptide Foldamers Based on Cis-β-Aminocyclopentanecarboxylic Acid. Berlicki, Ł.; Pilsl, L.; Wéber, E.; Mándity, I. M.; Cabrele, C.; Martinek, T. A.; Fülöp, F.; Reiser, O. Angew. Chemie - Int. Ed. 2012, 51 (9), 2208–2212. https://doi.org/10.1002/anie.201107702.
  • Stereoselective Synthesis of Pinane-Type Tridentate Aminodiols and Their Application in the Enantioselective Addition of Diethylzinc to Benzaldehyde. Csillag, K.; Németh, L.; Martinek, T. A.; Szakonyi, Z.; Fülöp, F. Tetrahedron Asymmetry 2012, 23 (2), 144–150. https://doi.org/10.1016/j.tetasy.2012.01.020.
  • A Foldamer-Dendrimer Conjugate Neutralizes Synaptotoxic β-Amyloid Oligomers. Fülöp, L.; Mándity, I. M.; Juhász, G.; Szegedi, V.; Hetényi, A.; Wéber, E.; Bozsó, Z.; Simon, D.; Benko, M.; Király, Z.; Martinek, T. A. PLoS One 2012, 7 (7). https://doi.org/10.1371/journal.pone.0039485.
  • Self-Association-Driven Transition of the β-Peptidic H12 Helix to the H18 Helix. Szolnoki, É.; Hetényi, A.; Martinek, T. A.; Szakonyi, Z.; Fülöp, F. Org. Biomol. Chem. 2012, 10 (2), 255–259. https://doi.org/10.1039/c1ob06627g.

2011

  • Physico-Chemical Characterization and in Vitro/in Vivo Evaluation of Loratadine:Dimethyl-β-Cyclodextrin Inclusion Complexes. Szabados-Nacsa, A.; Sipos, P.; Martinek, T.; Mándity, I.; Blazsó, G.; Balogh, A.; Szabó-Révész, P.; Aigner, Z. J. Pharm. Biomed. Anal. 2011, 55 (2), 294–300. https://doi.org/10.1016/j.jpba.2011.01.024.

2010

  • 15N and 13C Group-Selective Techniques Extend the Scope of STD NMR Detection of Weak Host-Guest Interactions and Ligand Screening. Kövér, K. E.; Wéber, E.; Martinek, T. A.; Monostori, É.; Batta, G. ChemBioChem 2010, 11 (15), 2182–2187. https://doi.org/10.1002/cbic.201000317.
  • Functionalization of Gold Nanoparticles with Amino Acid, β-Amyloid Peptides and Fragment. Majzik, A.; Fülöp, L.; Csapó, E.; Bogár, F.; Martinek, T.; Penke, B.; Bíró, G.; Dékány, I. Colloids Surfaces B Biointerfaces 2010, 81 (1), 235–241. https://doi.org/10.1016/j.colsurfb.2010.07.011.
  • Building β-Peptide H10/12 Foldamer Helices with Six-Membered Cyclic Side-Chains: Fine-Tuning of Folding and Self-Assembly. Mándity, I. M.; Fülöp, L.; Vass, E.; Tóth, G. K.; Martinek, T. A.; Fülöp, F. Org. Lett. 2010, 12 (23), 5584–5587. https://doi.org/10.1021/ol102494m.
  • Stereoselective Synthesis of Pinane-Based β- And γ-Amino Acids via Conjugate Addition of Lithium Amides and Nitromethane. Szakonyi, Z.; Balázs, Á.; Martinek, T. A.; Fülöp, F. Tetrahedron Asymmetry 2010, 21 (20), 2498–2504. https://doi.org/10.1016/j.tetasy.2010.09.009.
  • Galectin-1-Asialofetuin Interaction Is Inhibited by Peptides Containing the Tyr-Xxx-Tyr Motif Acting on the Glycoprotein. Wéber, E.; Hetényi, A.; Váczi, B.; Szolnoki, É.; Fajka-Boja, R.; Tubak, V.; Monostori, É.; Martinek, T. A. ChemBioChem 2010, 11 (2), 228–234. https://doi.org/10.1002/cbic.200900502.

2009

  • Efficient Synthesis of 3,4- and 4,5-Dihydroxy-2-Amino-Cyclohexanecarboxylic Acid Enantiomers. Benedek, G.; Palkó, M.; Wéber, E.; Martinek, T. A.; Forró, E.; Fülöp, F. Tetrahedron Asymmetry 2009, 20 (19), 2220–2225. https://doi.org/10.1016/j.tetasy.2009.09.001.
  • Stabilisation of Peptide Foldamers in an Aqueous Medium by Incorporation of Azapeptide Building Blocks. Hetényi, A.; Tóth, G. K.; Somlai, C.; Vass, E.; Martinek, T. A.; Fülöp, F. Chem. - A Eur. J. 2009, 15 (41), 10736–10741. https://doi.org/10.1002/chem.200900724.
  • Sculpting the β-Peptide Foldamer H12 Helix via a Designed Side-Chain Shape. Hetényi, A.; Szakonyi, Z.; Mándity, I. M.; Szolnoki, É.; Tóth, G. K.; Martinek, T. A.; Fülöp, F. Chem. Commun. 2009, No. 2, 177–179. https://doi.org/10.1039/b812114a.
  • Copper(Ii) and Zinc(Ii) Ion Binding Properties of a MAP Type Branched Ligand with Histidines as Surface Functionalities. Kolozsi, A.; Vosekalna, I.; Martinek, T.; Larsen, E.; Gyurcsik, B. Dalt. Trans. 2009, No. 29, 5647–5654. https://doi.org/10.1039/b903721g.
  • A Simple, Efficient, and Selective Deuteration via a Flow Chemistry Approach. Mándity, I. M.; Martinek, T. A.; Darvas, F.; Fülöp, F. Tetrahedron Lett. 2009, 50 (30), 4372–4374. https://doi.org/10.1016/j.tetlet.2009.05.050.
  • Design of Peptidic Foldamer Helices: A Stereochemical Patterning Approach. Mándity, I. M.; Wéber, E.; Martinek, T. A.; Olajos, G.; Tóth, G. K.; Vass, E.; Fülöp, F. Angew. Chemie - Int. Ed. 2009, 48 (12), 2171–2175. https://doi.org/10.1002/anie.200805095.
  • Távol a homokiralitástól, avagy a peptidomimetikumok önrendeződése. Martinek, T. Magy. TUDOMÁNY 2009, 170 (7), 782-788 PG – 7
  • Enhanced Oral Bioavailability of Loratadine via a PH-Independent Inclusion Complex. Nacsa, A.; Aigner, Z.; Sipos, P.; Martinek, T.; Blazsó, G.; Balogh, A.; Révész, P. Eur. J. Pharm. Sci. 2009, 38 (1, Suppl.), 3–97
  • Loratadin biohasznosíthatóságának növelése pH-független zárványkomplexek-képzéssel. Nacsa, Á.; Sipos, P.; Martinek, T.; Blazsó, G.; Balogh, Á.; Révész, P.; Aigner, Z. Gyogyszereszet 2009, 53 (Suppl. 1), S114-S114 PG-1

2008

  • Efficient Synthesis of Hydroxy-Substituted Cispentacin Derivatives. Benedek, G.; Palkó, M.; Wéber, E.; Martinek, T. A.; Forró, E.; Fülöp, F. European J. Org. Chem. 2008, 2008 (21), 3724–3730. https://doi.org/10.1002/ejoc.200800345.
  • Chromatographic Determination of Iridoids in Stachys Recta, and Investigation of Inorganic Elements by X-Ray Fluorescence Spectroscopy. Háznagy-Radnai, E.; Pintye-Hódi, K.; Czigle, S.; Martinek, T.; Janicsák, G.; Máthé, I.; Eros, I. J. Planar Chromatogr. - Mod. TLC 2008, 21 (1), 27–32. https://doi.org/10.1556/JPC.21.2008.1.4.
  • Cytotoxic Activities of Stachys Species. Háznagy-Radnai, E.; Réthy, B.; Czigle, S.; Zupkó, I.; Wéber, E.; Martinek, T.; Falkay, G.; Máthé, I. Fitoterapia 2008, 79 (7–8), 595–597. https://doi.org/10.1016/j.fitote.2008.06.009.
  • Ligand-Induced Flocculation of Neurotoxic Fibrillar Aβ (1-42) by Noncovalent Crosslinking. Hetényi, A.; Fülöp, L.; Martinek, T. A.; Wéber, E.; Soós, K.; Penke, B. ChemBioChem 2008, 9 (5), 748–757. https://doi.org/10.1002/cbic.200700351.
  • Structural Characterization of H[Cis or Trans)-ACPC-2S-Aza-ACPC](3)-NH2 Peptides. Hetényi, A.; Tóth, G.; Somlai, C.; Martinek, T.; Fülöp, F. J. Pept. Sci. 2008, 14 (8), 111-111 PG – 1
  • Stereoselective Synthesis of Hydroxylated β-Aminocyclohexanecarboxylic Acids. Kiss, L.; Forró, E.; Martinek, T. A.; Bernáth, G.; De Kimpe, N.; Fülöp, F. Tetrahedron 2008, 64 (22), 5036–5043. https://doi.org/10.1016/j.tet.2008.03.068.
  • Building Beta-Peptide Foldamers via Stereochernical LEGO Approach. Mándity, I.; Wéber, E.; Martinek, T.; Tóth, G.; Vass, E.; Fülöp, F. J. Pept. Sci. 2008, 14 (8), 1–86
  • Enantioselective Hydrogenation of Ketopantolactone Using Pt-β-ICN Chiral Catalyst: Correlation between the Solution-State Concentration of a Nucleophilic β-Isocinchonine-Ketopantolactone Complex and Enantioselectivity. Martinek, T. A.; Varga, T.; Balázsik, K.; Szöllosi, G.; Fülöp, F.; Bartók, M. J. Catal. 2008, 255 (2), 296–303. https://doi.org/10.1016/j.jcat.2008.02.020.
  • The Effect of the so Called “Beta-Sheet Breakers” (BSBs) on A Beta 1-42 Aggregates. Soós, K.; Fülöp, L.; Bozsó, Z.; Szegedi, V.; Martinek, T.; Zarándi, M.; Penke, B. J. Pept. Sci. 2008, 14 (8), 109-110 PG – 2
  • Regio- and Stereoselective Synthesis of Constrained Enantiomeric β-Amino Acid Derivatives. Szakonyi, Z.; Martinek, T. A.; Sillanpää, R.; Fülöp, F. Tetrahedron: Asymmetry 2008, 19 (19), 2296–2303. https://doi.org/10.1016/j.tetasy.2008.09.026.

2007

  • A New Rigid Cinchona Modified (α-IQ) Platinum Catalyst for the Enantioselective Hydrogenation of Activated Ketones: Data to the Origin of Enantioselection. Balázsik, K.; Martinek, T. A.; Bucsi, I.; Szollosi, G.; Fogassy, G.; Bartók, M.; Olah, G. A. J. Mol. Catal. A Chem. 2007, 272 (1–2), 265–274. https://doi.org/10.1016/j.molcata.2007.03.042.
  • Diterpenoids and Flavonoids from the Fruits of Vitex Agnus-Castus and Antioxidant Activity of the Fruit Extracts and Their Constituents. Hajdú, Z.; Hohmann, J.; Forgo, P.; Martinek, T.; Dervarics, M.; Zupkó, I.; Falkay, G.; Cossuta, D.; Máthé, I. Phyther. Res. 2007, 21 (4), 391–394. https://doi.org/10.1002/ptr.2021.
  • Performance of the General Amber Force Field in Modeling Aqueous POPC Membrane Bilayers. Jójárt, B.; Martinek, T. A. J. Comput. Chem. 2007, 28 (12), 2051–2058. https://doi.org/10.1002/jcc.20748.
  • NMR Spectroscopic and Theoretical Evidence of Cinchona Alkaloid- Ketopantolactone Complex Formation in Aprotic Solvents: Implications for the Mechanism of Pt-Catalyzed Enantioselective Hydrogenation of Activated Ketones. Martinek, T. A.; Varga, T.; Fülöp, F.; Bartók, M. J. Catal. 2007, 246 (2), 266–276. https://doi.org/10.1016/j.jcat.2006.11.033.
  • Synthesis and Steric Structure of Pyrrolidine- and Piperidine-Fused 1,3,4,2-Oxadiazaphosphinanes. Martinek, T. A.; Szolnoki, É.; Zalán, Z.; Fülöp, F. Arkivoc 2007, 2007 (5), 202–209. https://doi.org/10.3998/ark.5550190.0008.516.
  • Regio- and Stereoselective Synthesis of the Enantiomers of Monoterpene-Based β-Amino Acid Derivatives. Szakonyi, Z.; Martinek, T. A.; Sillanpää, R.; Fülöp, F. Tetrahedron Asymmetry 2007, 18 (20), 2442–2447. https://doi.org/10.1016/j.tetasy.2007.09.028.
  • β-Methyl Substitution of Cyclohexylalanine in Dmt-Tic-Cha-Phe Peptides Results in Highly Potent δ Opioid Antagonists. Tóth, G.; Ioja, E.; Tömböly, C.; Ballet, S.; Tourwé, D.; Péter, A.; Martinek, T.; Chung, N. N.; Schiller, P. W.; Benyhe, S.; Borsodi, A. J. Med. Chem. 2007, 50 (2), 328–333. https://doi.org/10.1021/jm060721u.
  • Substituent Effects in the Ring-Chain Tautomerism of 4-Alkyl-2-Aryl Substituted Oxazolidines and Tetrahydro-1,3-Oxazines. Juhász, M.; Lázár, L.; Fülöp, F. J. Heterocycl. Chem. 2007, 44 (6), 1465–1473. https://doi.org/10.1002/jhet.5570440635.

2006

  • Effect of Short Peptides on A Beta(1-42) Fibrils. Bozsó, Z.; Penke, B.; Fülöp, L.; Martinek, T.; Károlyné Lakatos, A.; Soós, K.; Laczko, I.; Zarándi, M. J. Pept. Sci. 2006, 12 (Supplement), 151-151 PG – 1
  • Development of a Chirality-Sensitive Flexibility Descriptor for 3+3D-QSAR. Dervarics, M.; Ötvös, F.; Martinek, T. A. J. Chem. Inf. Model. 2006, 46 (3), 1431–1438. https://doi.org/10.1021/ci0505574.
  • Application of Alicyclic β-Amino Acids in Peptide Chemistry. Fülöp, F.; Martinek, T. A.; Tóth, G. K. Chem. Soc. Rev. 2006, 35 (4), 323–334. https://doi.org/10.1039/b501173f.
  • Design, Synthesis and Investigation of Putative Beta-Amyloid Aggregation Inhibitors Based on the Sequence of Beta-Amyloid (30-34). Fülöp, L.; Zarándi, M.; Datki, Z. L.; Hetényi, A.; Martinek, T.; Károlyné Lakatos, A.; Soós, K.; Penke, B. J. Pept. Sci. 2006, 12 (S1), 211-211 PG – 1
  • The Cis-Trans Isomerisation of Homologous 2-Hydroxycycloalkanecarboxylic Acids under Basic Conditions. Gyarmati, C. Z.; Pálinkó, I.; Bokros, A.; Martinek, A. T.; Bernáth, G. Chinese J. Chem. 2006, 24 (12), 1792–1795. https://doi.org/10.1002/cjoc.200690335.
  • Secondary Structure of Hydrazino-Peptides with Cyclic Side-Chain. Hetényi, A.; Tóth, G.; Somlai, C.; Martinek, T.; Fülöp, F. J. Pept. Sci. 2006, 12 (S1), 197-197 PG – 1
  • Secondary Structure Dependent Self-Assembly of β-Peptides into Nanosized Fibrils and Membranes. Martinek, T. A.; Hetényi, A.; Fülöp, L.; Mándity, I. M.; Tóth, G. K.; Dékány, I.; Fülöp, F. Angew. Chemie - Int. Ed. 2006, 45 (15), 2396–2400. https://doi.org/10.1002/anie.200504158.
  • The Beta-Peptide Domain: From Controlled Secondary Structures to Nanostructured Assemblies. Martinek, T.; Mándity, I.; Hetényi, A.; Fülöp, L.; Toth, G. K.; Fülöp, F. J. Pept. Sci. 2006, 12 (S1), 1–93
  • Effects of the Alternating Backbone Configuration on the Secondary Structure and Self-Assembly of β-Peptides. Martinek, T. A.; Mándity, I. M.; Fülöp, L.; Tóth, G. K.; Vass, E.; Hollósi, M.; Forró, E.; Fülöp, F. J. Am. Chem. Soc. 2006, 128 (41), 13539–13544. https://doi.org/10.1021/ja063890c.
  • Long-Term Interaction between Beta-Amyloid Fibrils and Short Peptides. Penke, B.; Fülöp, L.; Martinek, T.; Bozsó, Z.; Laczko, I.; Károlyné Lakatos, A.; Soós, K.; Zarándi, M. J. Pept. Sci. 2006, 12 (S1), 156-156 PG – 1
  • Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by γ-Amino Alcohols Derived from (+)- and (-)-α-Pinene. Szakonyi, Z.; Balázs, Á.; Martinek, T. A.; Fülöp, F. Tetrahedron Asymmetry 2006, 17 (2), 199–204. https://doi.org/10.1016/j.tetasy.2005.12.011.
  • Vibrational and Criroptical Spectroscopic Investigations on Cis-2-Aminocyclopentanecarboxylic Acid Oligomers. Vass, E.; Hollósi, M.; Martinek, T.; Fülöp, F. J. Pept. Sci. 2006, 12 (Supplement), 204-204 PG – 1
  • Synthesis and Conformational Analysis of Tetrahydroisoquinoline- and Piperidine-Fused 1,3,4,2-Oxadiazaphosphinanes, New Ring Systems. Zalán, Z.; Martinek, T. A.; Lázár, L.; Sillanpää, R.; Fülöp, F. Tetrahedron 2006, 62 (12), 2883–2891. https://doi.org/10.1016/j.tet.2006.01.018.

2005

  • Facile Regio- and Diastereoselective Syntheses of Hydroxylated 2-Aminocyclohexanecarboxylic Acids. Fülöp, F.; Palkó, M.; Forró, E.; Dervarics, M.; Martinek, T. A.; Sillanpää, R. European J. Org. Chem. 2005, 2005 (15), 3214–3220. https://doi.org/10.1002/ejoc.200500062.
  • Chain-Length-Dependent Helical Motifs and Self-Association of β-Peptides with Constrained Side Chains. Hetényi, A.; Mándity, I. M.; Martinek, T. A.; Tóth, G. K.; Fülöp, F. J. Am. Chem. Soc. 2005, 127 (2), 547–553. https://doi.org/10.1021/ja0475095.
  • The 3D Structure of the Binding Pocket of the Human Oxytocin Receptor for Benzoxazine Antagonists, Determined by Molecular Docking, Scoring Functions and 3D-QSAR Methods. Jójárt, B.; Martinek, T. A.; Márki, Á. J. Comput. Aided. Mol. Des. 2005, 19 (5), 341–356. https://doi.org/10.1007/s10822-005-7137-0.
  • Ligand-Based Prediction of Active Conformation by 3D-QSAR Flexibility Descriptors and Their Application in 3+3D-QSAR Models. Martinek, T. A.; Ötvös, F.; Dervarics, M.; Tóth, G.; Fülöp, F. J. Med. Chem. 2005, 48 (9), 3239–3250. https://doi.org/10.1021/jm049157i.
  • Naftalinnal kondenzált 1,3-O,N-heterociklusok szintézise = Synthesis of naphthalene-condensed 1,3-O,N-heterocycles. Szatmári, I.; Lázár, L.; Martinek, T.; Fülöp, F. Magy. KÉMIAI FOLYÓIRAT - KÉMIAI KÖZLEMÉNYEK 2005, 111 (1), 7–18

2004

  • Resolution of Carvedilol’s Conformational Surface via Gas and Solvent Phase Density Functional Theory Optimizations and NMR Spectroscopy. Almeida, D. R. P.; Gasparro, D. M.; Martinek, T. A.; Fülöp, F.; Csizimadia, I. G. J. Phys. Chem. A 2004, 108 (38), 7719–7729. https://doi.org/10.1021/jp0403240.
  • TRUE FOLDING OF CONFORMATIONALLY CONSTRAINED Beta-PEPTIDES: CHAIN LENGTH-DEPENDENT SECONDARY STRUCTURE. Hetenyi, A.; Mándity, I.; Martinek, T.; Tóth, G.; Fulop, F. J. Pept. Sci. 2004, 10, 273-273 PG – 1
  • Synthesis of 2,4-Diaryl-3,4-Dihydro-2H-Naphth[2,1-e][1,3]Oxazines and Study of the Effects of the Substituents on Their Ring-Chain Tautomerism. Szatmári, I.; Martinek, T. A.; Lázár, L.; Fülöp, F. European J. Org. Chem. 2004, 2004 (10), 2231–2238. https://doi.org/10.1002/ejoc.200300753.
  • Stereoelectronic Effects in Ring-Chain Tautomerism of 1,3-Diarylnaphth[1,2-e][1,3]Oxazines and 3-Alkyl-1-Arylnaphth[1,2-e][1,3]Oxazines. Szatmári, I.; Martinek, T. A.; Lázár, L.; Koch, A.; Kleinpeter, E.; Neuvonen, K.; Fülöp, F. J. Org. Chem. 2004, 69 (11), 3645–3653. https://doi.org/10.1021/jo0355810.

2003

  • Synthesis and Stereochemistry of Azeto[2,1-a]Isoquinolin-2-One Derivatives. Csomós, P.; Martinek, T.; Lázár, L.; Fülöp, F. ARKIVOC 2003, No. 5, 7–87
  • Synthesis and Stereochemistry of Azeto[2,1-a]Isoquinolin-2-One Derivatives. Csomós, P.; Martinek, T. A.; Lázár, L.; Fülöp, F. Arkivoc 2003, 2003 (5), 87–93. https://doi.org/10.3998/ark.5550190.0004.509.
  • Substituent-Dependent Negative Hyperconjugation in 2-Aryl-1,3-N,N-Heterocycles. Fine-Tuned Anomeric Effect? Hetényi, A.; Martinek, T. A.; Lázár, L.; Zalán, Z.; Fülöp, F. J. Org. Chem. 2003, 68 (14), 5705–5712. https://doi.org/10.1021/jo034417+.
  • Side-Chain Control of β-Peptide Secondary Structures: Design Principles. Martinek, T. A.; Fülöp, F. Eur. J. Biochem. 2003, 270 (18), 3657–3666. https://doi.org/10.1046/j.1432-1033.2003.03756.x.
  • Substituent Effects in the Ring-Chain Tautomerism of 1,3-Diaryl-2,3-Dihydro-1H-Naphth[1,2-e][1,3]Oxazines. Szatmári, I.; Martinek, T. A.; Lázár, L.; Fülöp, F. Tetrahedron 2003, 59 (16), 2877–2884. https://doi.org/10.1016/S0040-4020(03)00331-4.
  • Synthesis and Conformational Analysis of 1,3,2-Diazaphosphorino[6,1-a] Isoquinolines, a New Ring System. Zalán, Z.; Martinek, T. A.; Lázár, L.; Fülöp, F. Tetrahedron 2003, 59 (46), 9117–9125. https://doi.org/10.1016/j.tet.2003.09.062.

2002

  • Ring-Chain Tautomerism of 2-Aryl-Substituted Cis- and Trans-Decahydroquinazolines. Lázár, L.; Göblyös, A.; Martinek, T. A.; Fülöp, F. J. Org. Chem. 2002, 67 (14), 4734–4741. https://doi.org/10.1021/jo020070j.
  • Cis-2-Aminocyclopentanecarboxylic Acid Oligomers Adopt a Sheetlike Structure: Switch from Helix to Nonpolar Strand. Martinek, T. A.; Tóth, G. K.; Vass, E.; Hollósi, M.; Fülöp, F. Angew. Chemie - Int. Ed. 2002, 41 (10), 1718–1721. https://doi.org/10.1002/1521-3773(20020517)41:10<1718::AID-ANIE1718>3.0.CO;2-2.
  • Synthesis of Imidazo[1′,5′:1,2]Pyrido [3,4-b]Indole Derivatives. Solymár, M.; Palkó, M.; Martinek, T.; Fülöp, F. Monatshefte fur Chemie 2002, 133 (11), 1423–1430. https://doi.org/10.1007/s007060200114.

2001

  • Synthesis and Stereochemistry of 4-Arylimino-1,3-Oxazino- and 1,3-Thiazino[4,3,a]Isoquinolines. Fülöp, F.; Martinek, T.; Bernáth, G. ARKIVOC 2001, No. 3, 7–33

2000

  • Synthesis and Stereochemistry of 1,3,2-Oxazaphosphorino [4,3-A]Isoquinolines. Fülöp, F.; Forró, E.; Martinek, T.; Günther, G.; Sillanpää, R. J. Mol. Struct. 2000, 554 (2–3), 119–125. https://doi.org/10.1016/S0022-2860(00)00662-1.
  • Reversibility of liosol <-> liogel <-> xerogel transformations, I. Martinek, T.; Lázár, L.; Fülöp, F.; Riddel, F. G. Magy. KÉMIAI FOLYÓIRAT - KÉMIAI KÖZLEMÉNYEK 2000, 106 (9), 347-353 PG – 7
  • The Conformations of Narasin-Metal Complexes in Solution Determined by NMR Spectroscopy. Martinek, T.; Riddell, F. G.; Wilson, C. F. J. Chem. Soc. Perkin Trans. 2 2000, 2000 (11), 2192–2198. https://doi.org/10.1039/b005618i.
  • The Conformations of Monensin-A Metal Complexes in Solution Determined by NMR Spectroscopy. Martinek, T.; Riddell, F. G.; Wilson, C.; Weller, C. T. J. Chem. Soc. Perkin Trans. 2 2000, 2000 (1), 35–41. https://doi.org/10.1039/a907984j.
  • Synthesis and Conformational Study of 1,3,2-Oxazaphosphorino[4,3- a]Isoquinolines: A New Ring System. Martinek, T.; Forró, E.; Günther, G.; Sillanpää, R.; Fülöp, F. J. Org. Chem. 2000, 65 (2), 316–321. https://doi.org/10.1021/jo991047+.
  • Synthesis and Transformations of Enantiomeric 1,2-Disubstituted Monoterpene Derivatives. Szakonyi, Z.; Martinek, T.; Hetényi, A.; Fülöp, F. Tetrahedron Asymmetry 2000, 11 (22), 4571–4579. https://doi.org/10.1016/S0957-4166(00)00435-3.

1999

1998

  • Synthesis and Steric Structure of Linearly-Fused Tetrahydroisoqinoline 1,3-Heterocycles. In 7th Blue Danube Symposium on Heterocyclic Chemistry; 1998
  • A Simple Synthesis of β-Alkyl-Substituted β-Amino Acids. Lázár, L.; Martinek, T.; Bernáth, G.; Fülöp, F. Synth. Commun. 1998, 28 (2), 219–224. https://doi.org/10.1080/00397919808005714.
  • The Structure of the Ionophoric Antibiotic Na-Tetronasin (M139603) in Solution. Martinek, T.; Riddell, F. G.; Rutherford, T. J.; Sareth, S.; Weller, C. T. Chem. Commun. 1998, No. 17, 1893–1894. https://doi.org/10.1039/a804482a.
  • Five-Component Equilibria of Ring-Chain Tautomeric Mixtures Derived from 2-Amino-1-Phenyl-1,3-Propanediol Diastereomers. Martinek, T.; Lázár, L.; Fülöp, F.; Riddell, F. G. Tetrahedron 1998, 54 (42), 12887–12896. https://doi.org/10.1016/S0040-4020(98)00780-7.
  • Five-component equilibria of ring-chain tautomeric mixtures derived from 2-amino-1-phenyl-1,3-propanediol diastereomers. Martinek, T.; Lázár, L.; Fülöp, F.; Riddell, F. G. Tetrahedron 1998, 54 (42), 12887–12896. https://doi.org/10.1016/S0040-4020(98)00780-7.

1997

  • Activation of Amorphous Cu-M (M = Ti, Zr or Hf) Alloy Powders Made by Mechanical Alloying. Molnár, Á.; Domokos, L.; Katona, T.; Martinek, T.; Mulas, G.; Cocco, G.; Bertóti, I.; Szépvölgyi, J. Mater. Sci. Eng. A 1997, 226228, 1074–1078. https://doi.org/10.1016/s0921-5093(96)10862-5.
  • Amorphous Alloy Catalysis IX. Isomerization and Hydrogenation of Allyl Alcohol over an Amorphous Copper-Zirconium Alloy. Martinek, T.; Molnár, Á.; Katona, T.; Bartók, M.; Lovas, A. J. Mol. Catal. A Chem. 1996, 112 (1), 85–92. https://doi.org/10.1016/1381-1169(96)00219-1.