The actions of neuropeptides on neurohormones and neurotransmitters
The aim of our study is to determine the effects of various neuropeptides (e.g. endomorphins and urocortins) on different neurohormones (e.g. CRH, AVP, oxytocin, ACTH and glucocorticoids) and neurotransmitters (e.g. serotonin, dopamine, GABA, glutamate and catecholamine), which play important role in stress and stress-related diseases (e.g. anxiety and depression).
The actions of addictive drugs on neurohormones and neurotransmitters
The aim of our study is to determine the effects of various addictive drugs (e.g. alcohol and nicotine) on different neurohormones (e.g. CRH, AVP and oxytocin) and neurotransmitters (e.g. dopamine, GABA, glutamate) which play important role in positive reinforcement (sensation of reward) and negative reinforcement (avoidance of reward deficit, anxiety and depression) induced by addictive drugs.
The aim of our study is to investigate the interaction of various addictive drugs (e.g. alcohol, nicotine, morphine) and neuropeptides (e.g. obestatin, ghrelin, leptin), since this interaction may have important consequences regarding drug addiction (e.g. increase of reward sensation, development of somatic or affective symptoms of withdrawal).