Final Program - May 24, 2002, Friday

National Theater

INVITED LECTURE: G.G. Persijn (Leiden, The Netherlands):
“Organ Transplantation in Europe”
08:30 - 09:00


Chairman/Introduction: F. Perner (Budapest, Hungary)


SYMPOSIUM 3
Organ Transplantation - State of the Art
09:00 - 10:40


Chairperson:
F. Perner (Budapest, Hungary)


S12
W. Land (Munich, Germany):
Kidney transplantation - State of the art

S13
F. Mühlbacher (Vienna, Austria):
Liver transplantation - State of the art

S14
T. Berney (Geneva, Switzerland):
Kidney-pancreas transplantation at the turn of the millenium - State of the art

S15
E. Wolner (Vienna, Austria):
Heart transplantation


Cinema I

SYMPOSIUM 5
Progress in Microcirculation Research
09:00 - 10:40


Chairperson:
K. Messmer (Munich, Germany)


S22
W.M. Kuebler (Berlin, Germany):
Imaging techniques in microcirculatory and vascular
biology studies of the intact rodent lung

S23
G. Szczesny (Warsaw, Poland):
Changes in the microcirculation of lower extremity
in response to direct mechanical trauma

S24
A. Szabó (Szeged, Hungary):
Analysis of the intestinal microcirculation

S25
E. Uhl (Aachen, Germany)
: Disturbances of cortical microcirculation in cerebral
hypoperfusion and ischaemia

S26
Z. Bajory (Szeged, Hungary):
The microcirculation of the urinary bladder

S27
F. Christ (Munich, Germany):
Clinical use of OPS imaging in neonates and patients undergoing cardio-pulmonary bypass


Cinema II

ORAL PRESENTATIONS
Hepatobiliary and Pancreatic Surgery (HPS)
09:00 - 10:40


Chairpersons:
H-W. Waclawiczek (Salzburg, Austria), R. Rintala (Helsinki, Finland)

84 The CD14+ class II+ blood cells reveal predilection to liver adenocarcinoma metastases
M. Stanczyk, Warsaw, Poland

85 Effect of cyclophosphamide and retinoic acid on hepatic metastasis following liver resection
J. Caramés, Leioa, Spain

86 The survival benefit of surgical treatment for recurrence of the remnant liver and lung after hepatic resection for colorectal metastases
H. Yoshidome, Chiba, Japan

87 Pringle maneuver improves lesion size in radiofrequency application. Experimental study in porcine in vivo model
F. Burdío, Zaragoza, Spain

88 Angiostatin inhibits experimental liver fibrosis
J.M. Vogten, Utrecht, The Netherlands

89 Receptor-mediated acceleration of hepatocellular transport system as measured by near-infrared spectroscopy
A. Tanaka, Kyoto, Japan

90 Estrogen has a potential role in the development of hepatopulmonary syndrome in rats
S. Yol, Konya, Turkey

91 The effect of tamoxifen and oophorectomy in preventing the development of hepatopulmonary syndrome in cirrhotic rats
S. Yol, Konya, Turkey

92 Importance of cytokines, NO and apoptosis in the pathological process of necrotising pancreatitis in rats
L. Leindler, Szeged, Hungary

93 Changes of quality of life and nutritional state in surgically treated patients with chronic pancreatitis
B. Tihanyi, Budapest, Hungary


National Theater

INVITED LECTURE: S. Nielsen (Aarhus, Denmark):
“Molecular Water Channels (Aquaporins) - Physiology and Pathophysiology”
11:00 - 11:30

Chairman/Introduction: T. Dóczi (Pécs, Hungary)

SYMPOSIUM 4
Central Nervous System Injury: Experimental and Clinical Approaches
11:30 -13:10


Chairpersons:
A. Büki (Pécs, Hungary), T. Dóczi (Pécs, Hungary)


S16
A. Kampfl (Innsbruck, Austria)
: Apoptotic and necrotic mechanisms in traumatic brain injury

S17
M. Rusnak (Vienna, Austria):
TBI epidemiology and characteristics of care in some countries of Europe

S18
E. Sulyok (Pécs, Hungary):
The structure and function of Na+-H+ exchanger with
particular reference to its involvement in brain volume regulation

S19
P. Bogner (Kaposvár-Pécs, Hungary)
: Some new aspects of cellular volume regulation: the role of intracellular proteins, osmotically inactive water and membrane fluidity

S20
Z. Vajda (Aarhus-Pécs, Denmark-Hungary):
Delayed intracellular water accumulation during the development of brain edema in aquaporin-4 deficient transgenic mdx mice

S21
A. Schwarcz (Pécs, Hungary):
Role of the NMR in the research of experimental brain edemas


Cinema I

SYMPOSIUM 6
Nitric Oxide and Vasoactive Mediators
11:30 - 13:10


Chairpersons:
H. Redl (Vienna, Austria), S. Bahrami (Vienna, Austria)


S28
P.K. Chatterjee (London, UK)
: Pathophysiological role of NO in different disease states

S29
A.V. Kozlov (Vienna, Austria):
NO detection - Different possible approaches

S30
C. Szabó (Beverly, USA)
: Pathways of cell death induced by peroxynitrite: relevance for the pathophysiology of circulatory shock - An update

S31
S. Bahrami (Vienna, Austria):
NOS independent NO generation and its pathophysiological relevance

S32
M. Bauer (Homburg/Saar, Germany):
NO and CO - Two endogenous vasodilators


Cinema II

ORAL PRESENTATIONS
Molecular Biology, Gene Therapy in Surgical Diseases (MB)
11:30 - 13:00


Chairpersons:
Y. Yamamoto (Kyoto, Japan), G. Kouraklis (Athens, Greece)

94 Effect of cycloprodigiosin on the induction of inducible nitric oxide synthase by interleukin-1b in primary cultured hepatocytes
S. Teshima, Moriguchi, Japan

95 Effect of pirfenidone on the induction of inducible nitric oxide synthase by inflammatory cytokine in hepatocytes
H. Nakanishi, Moriguchi, Japan

96 Stromal interaction upregulates gelatinase activity in pancreatic tumours in vitro
S.T. Ivanova, London, UK (presented by M. Khan)

97 Cepharanthine conquers P-glycoprotein-associated drug resistance in hepatocellular carcinoma cells
A. Nakajima, Kyoto, Japan

98 The prognostic significance of proliferating cell nuclear antigen in colorectal cancer. A prospective study with clinical correlation
R. Harisi, Budapest, Hungary

99 Identification and validation of candidate genes in pancreatic cancer
R. Grützmann, Dresden, Germany

100 Detection of occult tumour cells in bone marrow by reverse transcriptase-polymerase chain reaction (RT-PCR) in breast cancer patients
S. Dubecz, Budapest, Hungary

101 Differential gene expression profile in monocytes (M) from multiple injured patients
P. Biberthaler, Munich, Germany

102 Liver regeneration-biochemistry-insulin uptake-PCNA marking
T. Kotsis, Athens, Greece


Cinema III

ORAL PRESENTATIONS
New Surgical Techniques (NST)
11:30 - 12:30


Chairpersons:
I. Mikó (Debrecen, Hungary), G. Ussia (Bologna, Italy)


103 A systematic approach to the surgical treatment of gynaecomastia
B. Fruhstorfer, Cambridge, UK

104 An experimental model for alternative blood supply of the kidney in the aspect of renal function
T. Lesznyák, Debrecen, Hungary

105 A combination of endoscopic laser surgery and segment resection for the treatment of cricotracheal stenoses
Z. Bella, Szeged, Hungary

106 Laryngeal reinnervation in animal experiments
A. Tóth, Debrecen, Hungary

107 A new, minimally invasive treatment concept for the bilateral vocal cord paralysis – A prospective study
L. Rovó, Szeged, Hungary

108 The experimental examination of the healing process of telescopic anastomosis
G. Szûcs, Miskolc, Hungary


National Theater

POSTER SESSION I
Gastrointestinal Surgery
14:00 - 15:00


Chairpersons:
B. Jeppsson (Malmö, Sweden), G. Weber (Pécs, Hungary)


PP1 Evaluation of usefulness of enteral nutrition for three-field radical surgery and palliative surgery of esophageal carcinoma
M. Ohara, Hakodate, Japan

PP2 Roux-Y reconstruction after distal gastrectomy reduces IL-8 in the gastric remnant
K. Fukuhara, Osaka, Japan

PP3 Etiology and prevention of stomal prolapse in loop stoma
K. Maeda, Toyoake, Japan

PP4 Treatment of fecal incontinence and defecatory disturbances
K. Maeda, Toyoake, Japan

PP5 Contrast radiography for anastomotic integrity prior to reversal of defunctioning stoma - Does it change management?
A.A. Warsi, Llanttrisant, UK

PP6 Prevention of permanent colostomy
V. Sulyma, Dnipropetrovsk, Ukraine


POSTER SESSION II
Surgical Pathophysiology
14:00 - 15:00


Chairpersons:
T. Minor (Bonn, Germany), M. Sahin (Konya, Turkey)


PP7 Progenitor-like cells of islets from pancreatic ductal tissue fragments in three-dimensional culture system
A. Isogai, Kawasaki, Japan

PP8 The effect of mycophenolate mofetil on liver fibrosis in an experimental model
N. Sikas, Thessaloniki, Greece

PP9 The mid-term effectiveness of branched chain amino acid supplement in cirrhosis
H. Nozaki, Tokyo, Japan

PP10 The role of predicting factors in progression and response of patients with oesophageal cancer undergoing neoadjuvant therapy (an immunohistochemical study)
G. Bognár, Budapest, Hungary

PP11 Histochemical appearance and prognostic significance of Maackia amurensis leukoagglutinin-positive glycoconjugates in human gastric cancer
W. Tang, Tokyo, Japan

PP12 Expression of cell cycle control proteins in colon cancer and their correlation in prognosis
G. Kouraklis, Athens, Greece

PP13 Analysis of K-ras and p53 gene mutations in human colorectal carcinoma: relationship to clinicopathological variables
L. Zajac, Warsaw, Poland

PP14 Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human gastric carcinoma
K. Ogawa, Tokyo, Japan


POSTER SESSION III
Hepatobiliary and Pancreatic Surgery
14:00 - 15:00


Chairpersons:
G. Farkas (Szeged, Hungary), T.M. van Gulik (Amsterdam, The Netherlands)


PP15 Consideration of detection of Helicobacter pylori in the gastric mucosa as a respective factor for occurrence of acute attack of cholecystitis at a glance of asymptomatic cholecystolithiasis
N. Ueno, Osaka, Japan

PP16 Liver regeneration and angiogenesis in mice deficient for plasminogen
J.M. Vogten, Utrecht, The Netherlands

PP17 Anterior liver resections for surgical treatment of primary and secondary liver tumours
I. Takács, Debrecen, Hungary

PP18 Surgical impact of liver resections with microwave tissue coagulator
S. Satoi, Osaka, Japan

PP19 Experimental model of intraoperative radiotherapy on ischemic rat liver
O. Hahn, Budapest, Hungary

PP20 Pattern and risk of postoperative recurrence in solitary hepatocellular carcinoma
Y. Takada, Tsukuba, Japan

PP21 Hepatocyte growth factor level in liver and blood and post-operative liver cell proliferation in patients with benign and malignant liver tumors underwent partial hepatectomy
B. Lukomska, Warsaw, Poland

PP22 Antireflux effectivity of various porto-enterostomas
T. Cserni, Debrecen, Hungary

PP23 The effect of intraductal corticosteroid treatment on the experimental acute pancreatitis of dogs
L. Kerekes, Debrecen, Hungary

PP24 Clinicopathological evaluation of long and short-term survivors treated for pancreatic carcinoma
S. Takai, Osaka, Japan


POSTER SESSION IV
Sepsis and Inflammation
14:00 - 15:00


Chairpersons:
T. Zimmermann (Dresden, Germany), N. Marczin (Harefield, UK)


PP25 The effects of dimethylsulfoxide and pentoxifylline on plasma malondialdehyde levels and tissue damage in sepsis
S. Tekin, Konya, Turkey

PP26 The effects of selective iNOS inhibitory aminoguanidine on plasma NO levels, tissue damage and organ function in sepsis
M. Sahin, Konya, Turkey

PP27 Pirfenidone ameliorates endotoxin-induced liver injury after partial hepatectomy in rats
H. Tsuchiya, Osaka, Japan

PP28 The influence of probiotics in bacterial translocation
K. Kotzampassi, Thessaloniki, Greece

PP29 Diagnostic value of urine “biopyrrins” (bilirubin oxidative products) in severity of acute abdomen
Y. Tsuji, Saitama, Japan

PP30 Effect of octreotide on the oxidative stress of acute experimental pancreatitis
K. Kotzampassi, Thessaloniki, Greece

PP31 Tissue factor in the pathophysiology of patients with major trauma - role of NF-kB and AP-1
G. von Gagern, Dresden, Germany

PP32 ATP synthase and keratinocyte growth factor gene expression in experimental gastroesophageal reflux disease
K. Szentpáli, Szeged, Hungary

PP33 Pathophysiology of decrease in erythrocyte deformability in acute pancreatitis
B. Chmiel, Katowice, Poland


POSTER SESSION V
Shock and Ischemia-Reperfusion Injury
14:00 - 15:00


Chairpersons:
W-P. Klövekorn (Bad Nauheim, Germany), R.T. Smolenski (Harefield, UK)


PP34 Formation of peroxynitrite as a result of nitric oxide-superoxide interaction in ischemia and reperfusion - A clinical trial

D. Ockert, Dresden, Germany

PP35 The antioxidative effect of DHEA-S in vitro and in vivo - chemiluminometric determination of hydroperoxy-groups in lipoproteins
T. Zimmermann, Dresden, Germany

PP36 Characterization of a hemorrhagic/traumatic shock model in rats mimicking clinical settings
L. Szalay, Vienna, Austria

PP37 Comparison of granulocyte activation and leukocyte adhesion molecule expression through acute ischemia and prolonged reperfusion in open and closed chest dog model
J. Lantos, Pécs, Hungary

PP38 Relative antioxidant activity in relation with renal ischemia-reperfusion injury
K. Petõ, Debrecen, Hungary

PP39 Follow-up of red blood cell deformability after short hindlimb ischemia in rat
N. Németh, Debrecen, Hungary

PP40 Special adaptation of different measuring methods on experimental animals in the aspect of ischemia-reperfusion injuries
N. Németh, Debrecen, Hungary

PP41 Endothelin-A receptor antagonism reduces torsion-induced aspermatogenesis and microcirculatory failure in the rat
R. Varga, Szeged, Hungary

PP42 Akt activation protects rat liver from ischemia-reperfusion injury
N. Harada, Kyoto, Japan

PP43 Lower limb ischaemia-reperfusion induced remote hepatic injury is not altered by Kupffer cell depletion
A. Lewis, Belfast, Northern Ireland


POSTER SESSION VI
Organ Transplantation
14:00 - 15:00


Chairpersons:
T. Karatzas (Patras, Greece), N. Ohkohchi (Sendai, Japan)


PP44 Urinary trypsin inhibitor (UTI) exerts protective effects on the hepatic microvasculature in hypotensive brain-dead rats
T. Takahashi, Sagamihara, Japan

PP45 Diagnosis and treatment for the late vascular and biliary complications after living donor liver transplantation
N. Kawagishi, Sendai, Japan

PP46 Indication and efficacy of apheresis for the liver transplant recipients - Experiences of 22 cases in 52 LDLTx
N. Kawagishi, Sendai, Japan

PP47 Experimental study on hepatic reinnervation after orthotopic liver transplantation in rats
I. Sakamoto, Sagamihara, Japan

PP48 Dual kidney transplantation in the use of marginal donors
R. Cadrobbi, Padua, Italy

PP49 Omental flap harvesting for free transplantation. Preliminary data on the operative technique in dogs
J. Pap Szekeres, Kecskemét, Hungary

PP50 Histologic findings in small bowel tissue following pancreatico-duodenal allotransplantation with venous drainage into the portal or systemic circulation
U.J. Hesse, Ghent, Belgium


POSTER SESSION VII
Circulation
14:00 - 15:00


Chairpersons:
E. Rõth (Pécs, Hungary), W. Kübler (Berlin, Germany)


PP51 Pharmacological and ischemic preconditioning of pig hearts in the working heart model

W. Beierlein, Tübingen, Germany

PP52 Selective and immediate neuronal injury during cardiac surgery in domestic pig
Z. Tóth, Pécs, Hungary

PP53 Microcirculatory changes in ischemia-reperfusion-induced cystitis in rats
Z. Bajory, Munich, Germany

PP54 Strain and physical activity: determinants of lymph drainage in murines
M. Ionac, Timisoara, Romania

PP55 Effects of extracellular magnesium concentration on inflammatory stimulus induced enhancement of granulocyte MAC-1 avidity and affinity
H. Habazettl, Berlin, Germany

PP56 Effects of Celecoxib on the synovial microcirculation in mouse antigen-induced arthritis
H. Gebhard, Munich, Germany

PP57 Comparison of the circulatory effects of different hypertonic colloid volume expanders
E. Eszlári, Szeged, Hungary

PP58 Co-localization of the vanilloid VR1 and Trka receptors and substance P in neurons of the cochlear and vertebro-basilar arteries
Z. Vass, Szeged, Hungary


POSTER SESSION VIII
Traumatology and Tissue Repair
14:00 - 15:00


Chairpersons:
G. Szczesnyi (Warsaw, Poland), H-U. Spiegel (Münster, Germany)


PP59 Promotive effects of far-infra red ray on full-thickness skin wound healing

H. Toyokawa, Osaka, Japan

PP60 Therapeutic and prophylactic management of silicone gel sheeting (Epiderm) in hypertrophic and keloid scarring
O. Kelemen, Pécs, Hungary

PP61 (withdrawn)

PP62 Vascular tunnel concept in the acute surgical treatment of severe T-L1 fractures
A. Csókay, Budapest, Hungary

PP63 The treatment of polytraumatic patient’s diaphragm injuries
C. Oláh, Kecskemét, Hungary

PP64 Surgical security by limb replantation: an experimental amputat model
M. Szokoly, Debrecen, Hungary

PP65 Evaluation of monopolar and bipolar electrocoagulation in normal and abnormal coagulation status
M. Kontos, Athens, Greece


POSTER SESSION IX
New Techniques
14:00 - 15:00


Chairpersons:
I. Gál (Gyöngyös, Hungary), E. Antoniou (Athens, Greece)


PP66 Minimal invasive adrenal gland surgery - Chance and option
T. Jacobi, Dresden, Germany

PP67 Anaesthesiological management for swine laparoscopic experimental surgery
O. Toma, Timisoara, Romania

PP68 (withdrawn)

PP69 The electric oscillating brush dissection instrument: evaluation of vascular trauma and clinical applications for laparoscopic cholecystecomy and colectomy
M. Kakihara, Saitama, Japan

PP70 Comparison of different anastomotic techniques in tracheal replacement
Z. Szántó, Pécs, Hungary

PP71 Experiences with the retrograde percutaneous translaryngeal tracheotomy (Fantoni) on a surgical intensive care unit
R. Konopke, Dresden, Germany

PP72 Validation of a skills course using objective measures of technical ability
M.S. Khan, London, UK

*80 The ileo-aortic patch. Original experimental enterovasculoplasty on dog.
S. Neagu, Bucharest, Romania

* late registration


POSTER SESSION X
Molecular Biology and Immunology
14:00 - 15:00


Chairpersons:
T. Jánossy (Szeged, Hungary), H. Thorlacius (Malmö, Sweden)


PP73 Bioluminometric TC-assay in cases of gynaecology malignancies - Useful as pretherapeutical factor?
S. Albrecht, Dresden, Germany

PP74 Suppression of proliferative cholangitis by E2F decoy oligodeoxynucleotide
M. Yoshida, Kyoto, Japan

PP75 Participation of ERCC1 in resistance against cisplatin for human esophageal cancer cell lines
T. Miyahara, Kobe, Japan

PP76 Severe tissue injury alters self-regulation of neutrophil phagocytosis
G. Pap, Budapest, Hungary

PP77 Enhancement of circulating dendritic cell activity by immunomodulators (OK432 and KP-40)
H. Yanagimoto, Osaka, Japan

PP78 Activation of RET tyrosine kinase modulates IL-8 production
N. Iwahashi, Nagoya, Japan

PP79 Modification of the endotoxin-induced inflammatory cell response by glucocorticoids
J. Szakács, Szeged, Hungary


National Theater

INVITED LECTURE: J-L. Vincent (Brussels, Belgium):
“Update on Sepsis: Pathophysiology and Treatment”
15:00 -15:30


Introduction/Chairman: H. Redl (Vienna, Austria)


SYMPOSIUM 7
Sepsis - Pathophysiology and Treatment
15:30 - 17:10


Chairpersons: S. Bahrami (Vienna, Austria), W. Fürst (Vienna, Austria)


S33
W. Fürst (Vienna, Austria):
The innate axis - LPS as initiating principle

S34
B. Holzmann (Munich, Germany):
The innate axis - contribution of immunosuppression to outcome

S35
E. Faist (Munich, Germany):
Possible measures to overcome immunosuppression

S36
A.W. Rijneveld (Amsterdam, The Netherlands):
Contribution of humoral cascade activation to outcome

S37
A. Spittler (Vienna, Austria):
Monitoring possibilites


Cinema I

ORAL PRESENTATIONS
Shock and Ischemia-Reperfusion II (SHIR-2)
15:30 - 17:10


Chairpersons:
D. Mercer (Houston, USA), M.D. Menger (Homburg, Germany)


61 (withdrawn)

62 Antithrombin III substitution inhibits local intravascular coagulation and fibrin deposition after intestinal ischemia in rats
E.H.P. Roossink, Amsterdam, The Netherlands

63 Antioxidants and ischemia-reperfusion of the rat intestine in the absence of leucocytes
I. García-Alonso, Leioa, Spain

64 Changes of the red blood cells deformability caused by mesenteric ischemia-reperfusion injury. An experimental animal study
E. Bráth, Debrecen, Hungary

65 Ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon: importance of P-selectin, lymphocyte function antigen-1 and CXC chemokines
A.A. Riaz, Malmö, Sweden

66 In vivo neuronal nitric oxide synthase stimulation protects intestinal ischemic injury
A. Sola, Barcelona, Spain

67 Hemodynamic effect of intestinal nitrite under normoxic and hypoxic conditions
L. Szalay, Vienna, Austria

68 Adenosine/xanthine level modulates NO generation and tissue injury in renal ischemia
J. López-Martí, Barcelona, Spain

69 Thromboxane release in ischemia and reperfusion injury studied by microdialysis
M. Ionac, Timisoara, Romania

70 Gender differences in neutrophil priming and oxidative injury following trauma and hemorrhagic shock
B. Toth, Birmingham, USA


Cinema II

ORAL PRESENTATIONS
Immunology (IM)
15:30 - 16:50


Chairpersons:
D.J. Bouchier-Hayes (Dublin, Ireland), L. Baranyi (Washington, USA)


109 Chimerism and tolerance through vascularized bone marrow transplantation: fact or fiction?
M. Vossen, Utrecht, The Netherlands

110 Mast cell-dependent neutrophil recruitment in the skin is importantly mediated by KC and LFA-1: inhibitory mechanisms of action of dexamethasone
R. Schramm, Malmö, Sweden

111 Conditioning of donor graft with recipient bone marrow cells predisposes for acute rejection
M. Maksymowicz, Warsaw, Poland

112 Studies on the role of T cells and T cell subclasses in graft rejection
T. Jánossy, Szeged, Hungary

113 Studies on the prevention of graft-versus-host disease (GVHD) by in vitro pretreatment of donor cells with anti-T cell antibodies
L. Szalai, Szeged, Hungary

114 Physiological roles of Kupffer cells in liver injury
G. Lázár, Szeged, Hungary

115 Changes in immune defence and heat-shock protein 70 level in the various stages of tuberculosis
J. Furák, Szeged, Hungary

116 Methotrexate as an immunosuppressive agent in a life-supporting hDAF pig-to-primate xenotransplantation model
R. Cadrobbi, Padua, Italy

 


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